AMR 2022
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Mobilising political commitment and action on antimicrobial resistance
Without a long-term and multisectoral response to AMR, the prevalence and impact of drug-resistant pathogens — on human, animal and plant health; environmental ecosystems; food production; livelihoods; and economies — will inevitably grow. The Global Leaders Group (GLG) on antimicrobial resistance (AMR) was established in 2020 to advocate for and help mobilise greater political commitment...
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Cooperate at a large scale or fail: the tragedy of antimicrobial resistance
Antimicrobial resistance (AMR) is a priority — yet an unresolved — global health problem. Antimicrobials have helped reduce the individual and societal impact of many diseases. Therefore, the loss in the ability to effectively prevent and treat infections with antimicrobials that follows from a rise in AMR will significantly reduce the advantages achieved in modern...
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Holistic infection management: tackling the challenge of sepsis and AMR
When considering how to better address sepsis – which already affects 250,000 people in the UK each year, with 52,000 people dying as a result, we need to consider infection management holistically.1 The growing threat of antimicrobial resistance (AMR) is a critical public health concern and a major challenge in the treatment of sepsis. As...
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How can diagnostic tests help with antimicrobial resistance in the UK?
Tackling antimicrobial resistance (AMR) is truly like fighting a monster with many heads — AMR is a global threat, much like climate change with many causes and no single solution even for each country. Diagnostic tests are an important tool to help reduce AMR. These tests are done on samples from the body such as...
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Biggest AMR dilemma: to give, or not to give antibiotics?
The misdiagnosis of sepsis is leading to an overuse of antibiotics, but early and accurate diagnostics using point-of-care biomarkers can address this problem. The two main reasons for the use of antibiotics are the treatment and the prevention of bacterial infections. Overuse of antibiotics Sepsis (a dysregulated reaction of the body to infection with 50...
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How can rapid, effective diagnostics help in the fight against antimicrobial resistance?
Accurate, rapid infection diagnosis supports healthcare teams to get people the care they need quickly and reduce the impact of AMR. Antimicrobial resistance (AMR) is a widespread concern in the UK; we must use current antimicrobials wisely to reduce the risk of AMR infections to patients. Accurate, rapid diagnostic tests support healthcare teams to identify...
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The role of the environment in the fight against AMR
Much of the global coordination on combatting AMR has rightly been focused on incentives, appropriate use, stewardship, diagnostics and other tools. But we must also consider the environmental dimension of antimicrobial resistance. With over 100 members, the AMR Industry Alliance is the largest life-sciences coalition providing sustainable solutions to curb AMR, including awareness raising and...
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Seizing the opportunity of UNGA 2024 for bold commitments to AMR
We must strengthen our efforts to make the 2024 political commitment a game-changer with specific and bold commitments for the response to antimicrobial resistance. The 2016 Political Declaration of the High Level Meeting (HLM) of the United Nations General Assembly (UNGA) on antimicrobial resistance (AMR) was a milestone that brought a paradigm shift in the...
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Why we must work together to combat the threat of AMR
Pharmaceutical companies have joined forces to launch an action fund which aims to incentivise investment in antibiotic R&D and address the global threat of antimicrobial resistance. Antimicrobial resistance (AMR) is an alarming wake-up call — with the potential to set healthcare back by decades. “We can’t afford to underestimate the impact of AMR on global...
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The antibiotics market failure: Europe at a risky crossroad
In 2019, 4.95 million deaths were associated and 1.27 million were directly attributable to bacterial antimicrobial resistance (AMR). While the development of new effective antibiotics is crucial to respond to raising levels of AMR, the market for new antibiotics is broken. On top of scientific difficulties, current market-based incentives have largely failed to make antibiotics...
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