Global Cause
In this issue
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How unreliable UTI testing methods put women at risk — and drive AMR
The blind spots of current diagnostics for urinary tract infections leave much room to improve antimicrobial stewardship and women’s health. It’s time for innovation and change. Urinary tract infections (UTIs) are extremely common, and most women will experience at least one in their life. If left untreated, they can progress to serious kidney infections and...
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Why patient voices matter in the fight against drug-resistance infections
Including patient voices in addressing antimicrobial resistance (AMR) and advocating for improved treatments and policies can help combat drug-resistant infections. Antimicrobial resistance is one of the greatest health threats facing the UK and the world. Without swift and coordinated action, infections that were once manageable could again become life-threatening. Prioritising patient perspectives At Antibiotic Research...
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Why antimicrobial resistance and the changing climate are interconnected
To effectively combat antimicrobial resistance (AMR) and climate threats, we must adopt a holistic approach that recognises the intricate links between human, animal and environmental health. As AMR and the changing climate converge, their interconnectedness becomes clear. The climate crisis accelerates global warming, facilitating the spread of infectious diseases in new areas. Rising temperatures, rising...
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From farm to fork: curbing antimicrobial resistance in agrifood systems
Antimicrobial resistance (AMR) is a global health crisis, and sustainable farming practices are essential to reduce its spread. Farms and agrifood systems are pivotal in shaping how we address this challenge. Agriculture, particularly the prudent and responsible use of antimicrobials in livestock, plays a significant role in addressing AMR. Farms are often the first point...
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Combatting AMR: the need for environmental action and global collaboration
A global response to antimicrobial resistance requires cross-sector collaboration, focusing on environmental interventions. This is essential to preserve our ability to treat diseases in humans, animals and plants; ensure food safety and security; and protect the environment. Antimicrobial resistance (AMR) is one of the top 10 threats to global health and development, projected to cause...
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UK’s subscription model is a small step in the long fight against AMR
The UK has launched the first-ever market incentive to support the development of new antimicrobials. Without further commitments by other countries, there will be no impact on the AMR innovation ecosystem. Even though political declarations in support of AMR innovation are accumulating (UN General Assembly, G7 Communiqué), it is still as difficult as ever to...
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Call for industry-wide action and standards to fight AMR
Innovative pharmaceutical companies that make antibiotics are taking steps to reduce the negative potential consequences of AMR pollution in their manufacturing processes. Antimicrobial resistance (AMR) is often referred to in the future tense as if it’s a brewing healthcare crisis. We have to get real, insists Rex Clements, CEO of antibiotic manufacturer, Centrient Pharmaceuticals. AMR...
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How generative AI is transforming antibiotic discovery
Scientists are employing the latest advances in artificial intelligence — along with innovative funding approaches — to accelerate the pace of antibiotic discovery. In drug discovery, AI is becoming a pioneering force for good. For example, Phare Bio, a social venture founded in 2020, uses generative AI to develop novel antibiotics in partnership with Jim...
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Leveraging diagnostics and multisectoral partnerships in the global fight against AMR
While new data suggest that annual deaths attributable to antimicrobial resistance (AMR) will rise from 1.14 million in 2021 to 1.91 million in 2050,1 collective action is urgently needed including access to essential diagnostic tools. The economic implications of AMR are astounding too — with potential GDP losses of up to $3.4 trillion annually by...
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Why rapid diagnostics are key to fight climate-driven health threats
Rising temperatures and changing weather patterns are having a devastating impact on global health, making the accessibility of precise diagnostics even more important. Arguably, one of the biggest impacts of climate change isn’t talked about enough: the devastating effect rising temperatures and changing weather patterns have on human health. Increasing vector-borne diseases “In particular, vector-borne...