Global Cause
Infectious Diseases 2021
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Priorities in a pandemic: What’s next for access to TB care?
The focus on the COVID-19 response could lead to a global setback of at least 5 to 8 years for other infectious diseases, resulting in over a million additional deaths from TB alone. The declaration of a pandemic in March 2020 by the World Health Organisation (WHO) set off a chain of reactions. In rapid...
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Why AMR is a major threat to humanity
The growing threat of antibiotic resistance could lead to the collapse of modern medicine and worsen our abilities to fight infectious diseases unless new approaches are implemented. While pharmaceutical companies have “extraordinary knowledge” to develop antibiotics to tackle infection, imprecise use is creating antimicrobial resistance (AMR) and meaning some drugs are becoming less effective, leaving...
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Sexual health & the pandemic: Capitalising on a once in a lifetime opportunity
2020 brought unprecedented challenges for all working within sexual and reproductive health; staff grappled with maintaining essential service delivery during periods of varying lockdown and restrictions, whilst also responding to the immediate predations and consequences of COVID-19 itself. The response to these challenges has been remarkable across the healthcare system. Build back better We now...
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Sepsis: why new technology is needed to battle the silent killer
Sepsis, a syndromic response to infection and frequently a final common pathway to death for many infectious diseases, accounts for almost 20% of all global deaths. Only fast, targeted treatment can be sure to keep patients safe. A third of hospital deaths are due to sepsis, and rising. The World Health Organization (WHO) projects that...
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Helping biotechs ensure a successful vaccine journey
Biotech companies starting the vaccine development journey need to look at the whole process right from the start. “Research shows that about 22% of novel therapeutics never progress beyond their first clinical trials, for various reasons. This includes lack of commercially viability,” says Menzo Havenga, CEO, Batavia Biosciences. Contract development and manufacturing organisations (CDMOs) typically...
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Looking for ways to support the recovery of NHS diagnostic services
The pandemic has increased the backlog of people waiting for diagnostic tests. New ways of delivering these services are needed to increase efficiency and keep patients safe. In 2019, the NHS Long Term Plan — a report from frontline health and care staff, patients and other experts — identified the need for a radical overhaul...
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How we can learn from long COVID for Lyme disease
The large number of people with long COVID, many of them health professionals, has facilitated recognition of this complex condition. Just one year on there are NICE guidelines, SNOMED codes, specialist clinics and a research agenda. Those with long-standing, persistent symptoms from Lyme disease look on with interest. Currently dismissed from follow up and with...
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Protecting the world from the pandemics of the future
The effects of COVID-19 will be felt for generations, but the virus could be the wake-up call we need to respond quickly and effectively to the next big threats. Launched in 2017, the Coalition for Epidemic Preparedness Innovations (CEPI) has overseen breakthroughs in vaccine development including advancing the first ever Nipah and Lassa virus vaccines...
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Why working together is the best way to beat infectious disease
The global pandemic has shown there is no use trying to control infectious diseases in isolation. Collaborative international expertise and trust will be vital in the years ahead. After the catastrophe of the last year, is the world finally getting the message? To successfully fight infectious diseases, it’s not enough to have pockets of awareness...
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Humans’ oldest foe: fighting malaria in the face of resistance
Early markers of drug resistance have been identified in Africa, threatening the long-term efficacy of first line treatments in the continent, which bears around 93% of the global burden of the disease. The total malaria deaths in Africa almost halved between 2000 and 2019, with the fight against the disease focused on three key elements....