Global Cause
Antimicrobial Resistance 2020
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There’s new life in tried-and-tested drugs
A vital class of antibiotics is on the verge of being saved thanks to European investment and collaboration. An estimated 500 million daily doses of a class of antibiotics known as aminoglycosides are prescribed globally every year to fight bacterial infections. Their effectiveness is being undermined by antimicrobial resistance. Swiss-based Juvabis are currently progressing a...
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The threat of a bacterial pandemic needs a new business model now
Bacterial infections could become the next pandemic – and we could be helpless because today’s antibiotic development model is broken. “The World Health Organization (WHO) says 12% of current deaths are due to infections, and an estimated nine different bacteria are developing antimicrobial resistance. By 2050, that could mean 10 million deaths annually at a...
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Does nature hold the key to a future free of AMR?
The power of natural viruses in fighting harmful bacteria in humans and animals can finally be harnessed thanks to new technological advances. Phages have been around for billions of years – well before humans first stepped on the earth – and they are everywhere. On each of your hands there are trillions of these microscopic...
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AMR is a responsibility for us all: Global collaboration is the solution
Bacteria know no borders – which is why tackling AMR requires global collaboration by pharma companies, governments, healthcare systems and communities. Pharmaceutical companies are working to stem the rise of antimicrobial resistance (AMR), but success requires a cooperative approach. Amalia Adler-Waxman, who leads Environmental, Social and Governance (ESG) at Teva, says: “As one of the...
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Updates to the Core Elements of Hospital Antibiotic Stewardship Programs
Optimising the use of antibiotics is critical to effectively treat infections, protect patients from harm caused by unnecessary antibiotic use, and combat antibiotic resistance. Antibiotic stewardship programs can help clinicians improve clinical outcomes and minimise harm by improving the prescription of antibiotics. In 2019, Centers for Disease Control and Prevention (CDC) updated the hospital Core...
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Learning the hard way – what COVID-19 teaches us about the need for new medicines
AiCuris is acting now, building a solid pipeline of new anti-infective treatments and having launched its Pandemic and Resistance Emergency Preparedness (PREP) initiative. Until recently, most people have had no experience of diseases for which there are no medicines and that heavily impact the lives of a whole population. But since the arrival of COVID-19,...
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International collaboration tackling the next global health crisis
A pharmacy-led global health partnerships approach can be effective for supporting antimicrobial stewardship and tackling antimicrobial resistance. Multisectoral (One-Health) and multi-country approach essential The same or similar antimicrobial medicines may be used to treat infectious diseases in humans and animals. Also, resistant bacteria arising in humans, animals or the environment may spread from one to...
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Why drug-resistant tuberculosis poses a major risk to global health security
3 questions to Dr. Eliud Wandwalo, Head of TB at the Global Fund to Fight Aids, Tuberculosis and Malaria. What is drug-resistant tuberculosis? Drug-resistant tuberculosis (DR-TB) is a form of antimicrobial resistance that is difficult and costly to treat. It is caused by tuberculosis (TB) bacteria that are resistant to at least one of the...
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How to stop a hidden pandemic
The UK’s global partnerships are fighting against drug resistance. Antimicrobial resistance (AMR) is happening right now across the world. The United Nations and its member countries are committed to ensuring healthy lives for all by 2030 – which is only ten years away. The Sustainable Development Goals depend on us ensuring everyone, everywhere is safe...
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Employing the power of the microbiome in the fight against AMR
To preserve the utility of antibiotics, the world needs to change its approach to treating disease. A potential way forward is by harnessing the power of the human microbiome. It’s all so depressingly predictable, says Per Falk, President of biopharma company Ferring Pharmaceuticals. Mankind has misused — and over-used — life-saving antibiotics, reducing their effectiveness...